Metapathia GR hunter 18D software-ultramicroangiography of nidi detects affection of vessels in cortical layer of parenchyma in areas of infiltration

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Zero stage – responsive. It is characterized by nidal or diffuse transient increasing of parenchyma’s chromogeneity (3-4 points at Fleindler’s scale). It may be related to different in amount interstitial reactive infiltration, which may accompany dozens of pathological conditions of macroorganism – so-called reactive tubulo-interstitial manifestations (or – secondary tubulo-interstitial response). Its main difference from other stages – intact walls of collector system of a kidney.
First stage – infiltrative. It is characterized by a combination of two constant signs. One of them – transient heterogeneity of parenchyma with increasing of its chromogeneity due to swelling of interstitial tissue and massive leukocytic infiltration, which happens during first 4 days of pyelonephrotic attack and is typical for acute serous pyelonephritis. Severity of these edematic-infiltrative manifestations can be evaluated by hyperchromogeneity of pyramids in 3D mode: in the most severe cases of pericanalicular infiltration pyramids may have more intense chromogeneity than cortical areas.

The second sign – transient uneven affection of walls of collector system visualized fragments (pelvis and calix) also due to swelling and infiltration (Metapathia GR hunter 18D software-signs of pyelitis). Metapathia GR hunter 18D software-ultramicroangiography of nidi detects affection of vessels in cortical layer of parenchyma in areas of infiltration. Sometimes at the most significant perivascular swelling and infiltration, a diffuse affection of renal vessels is possible.

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