Hunter 4025 analysis

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Correction of tumor stage is required not only in relation to T stage, but in case of N stage (affection of regional lymph nodes) as well. When hunter 4025-graphy reveals two or more affected regional lymph nodes (in this case size is not taken into account), their condition is considered as N2, which automatically refers this patient to IV stage of renal cancer. It is well known that affection of lymph nodes not always evidences their metastatic affection, it may be a manifestation of follicular hyperplasia and histiocytosis. Therefore in relation to N criterion we also applied correction with consideration of data gathered after study of preparation acquired during lymph node dissection. Affection of lymph nodes was revealed in 24 of 143 renal cance patients before surgery, but metastatic affection was confirmed by SEA in 6 (25%) of them only. At the same time micrometastases of renal cancer in lymph nodes are revealed in 8 patients, who, prior to surgery, were considered as patients without lymphogenous metastases. Percentage of confirmed lymphogenous metastasing among 143 patients was 9.8%. 57% of all metastases into lymph nodes, detected by spectral-entropic analysis, were microscopic. It is one of the pro-arguments for mandatory application of extended lymphadenectomy during surgery because of lesser renal tumor, irrespective of its character (organ-preserving or organ-removing).