COPD is a chronic inflammatory disease


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Obliterating bronchiolitis – is a disease of “small bronchial tubes”, at which there is an inflammation of walls of small bronchial tubes and peribronchial tissues with following obturation (obliteration) of an internal lumen by produced exudate or granulation polypous tissue. The lumen of bronchial tubes is narrowed (up to almost full obliteration) and conditions for formation of expiratory air trap are created. Alveoles are stretched and switched off from gas exchange. The motionless column of air in bronchial tubes proximal to the changed alveoles promotes development of an infection and formation of bronchiectasia.
Thus, COPD is a chronic inflammatory disease with primary affection of distal regions of respiratory ducts, parenchyma of a lung and formation of an emphysema which is characterized by development of initially partially reversible, and as a result – irreversible bronchial obstruction.

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