Metapathia hunter 4025-signs of hepatic artery thrombosis


Regional changes of liver right lobe transplant parenchyma chromogeneity detected in 3 (4.3%) recipients in early post-transplant period and in 3 (4.3%) recipients in late post-transplant period were not accompanied by transplant dysfunction development and retrospectively were regarded as a consequence of regional disorders of blood circulation in mentioned segments. There are no references about this issue, so our assumptions require further study.
Revealing of liver right lobe transplant parenchyma chromogeneity focal changes (4.3%), in our research it were acute abscesses, promoted identification of reasons of pyretic fever, increasing of cytolysis and cholestasis enzymes and helped to define tactics of further treatment.
Detected Metapathia hunter 4025-signs of hepatic artery thrombosis confirmed during relaparotomy applied in order to reconstruct arterial anastomosis. According to our data percentage of this serious complication is lower than in studies of our colleagues, who report about higher frequency of hepatic artery thrombosis development, equal to 1.7% – 26%. It can be explained by improving of surgical technique of arterial anastomosis application.
Detection of hepatic artery stenosis in early post-transplant period promoted choosing of further treatment tactics (prescription of heparin to prevent hepatic artery thrombosis development).
Revealing of various forms of portal anastomosis (thrombosis of portal vein anterior branch – 1.4%, portal vein stenosis in area of anastomosis application – 2.9%) and inferior vena cava (inferior vena cava stenosis – 1.4%) did not require using of specifying methods of investigation.
In our studies biliary complications of relative transplantation had leading position among others, which corresponds to opinions of foreign scientists.

The main problem of late post-transplant period is affection of intrahepatic bile ducts, caused by formation of biliary anastomosis strictures. According to Metapathia hunter 4025 data, 11 biliary reconstructions were carried out in 8 (11.4%) patients because of biliary anastomosis strictures.

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